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Search Results for " chemokine (c-x-c motif) ligand 8 "

2

抑制剂 & 化合物

21

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T83712 Interleukin-8 (54-72) (human) TFA

IL-8 (54-72),C-X-C Motif Chemokine Ligand (54-72),CXCL8 (54-72)

Interleukin-8 (IL-8) (54-72) 对应于成熟人类IL-8序列的第54至72个氨基酸以及预处理序列的第81至99个氨基酸的肽。它抑制了初级人类中性粒细胞基于流动的黏附至人类脐静脉内皮细胞(HUVECs)。
T83841 STING Agonist D61

D61,Stimulator of Interferon Genes Agonist D61

STING激动剂D61(D61)是干扰素基因刺激剂(STING)的激动剂。它在基于细胞的分析中诱导IFN3诱导的分泌性碱性磷酸酶(SEAP)报告基因和IFN-β诱导的报告基因的表达(EC50分别为52.9和116 nM)。D61(4, 6, 和8 µM)增加了编码IFN-β和化学因子(C-X-C基序)配体10(CXCL10)的mRNA的表达以及TANK结合激酶1(TBK1)、IRF3和STING在THP-1单核细胞中的磷酸化。在体内,D61(每隔一天0.25 mg/kg)在CT26小鼠结肠癌模型中减少肿瘤体积,而不影响体重。

化合物

Interleukin-8 (54-72) (human) TFA
Cat.No: T83712
Synonym: IL-8 (54-72),C-X-C Motif Chemokine Ligand (54-72),CXCL8 (54-72)
Target:
STING Agonist D61
Cat.No: T83841
Synonym: D61,Stimulator of Interferon Genes Agonist D61
Target:
Cat. No. Product Name Species Expression System
TMPY-00472 IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99)

NAF,GCP1,NAP1,chemok...

Human E. coli
IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99) is expressed in E. coli expression system. The predicted molecular weight is 8.5 kDa and the accession number is A0A024RDA5.
TMPY-04726 IL-8/CXCL8 Protein, Human, Recombinant (His)

Interleukin-8,GCP1,MONAP,LE

Human P. pastoris (Yeast)
IL-8/CXCL8 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 9.8 kDa and the accession number is A0A024RDA5.
TMPY-00754 IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99)

MONAP,MDNCF,NAP-1,白介素,NAP1,LUC

Human HEK293 Cells
IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99) is expressed in HEK293 mammalian cells. The predicted molecular weight is 8 kDa and the accession number is A0A024RDA5.
TMPY-00279 Dengue virus DENV-2 (strain New Guinea C) NS5 (methyltransferase domain)/Nonstructural protein 5 Protein (His)

chemokine (C-

DENV E. coli
Dengue virus DENV-2 (strain New Guinea C) NS5 (methyltransferase domain)/Nonstructural protein 5 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 35.5 kDa and the accession number is AAC59275.1.
TMPY-03022 IL-8/CXCL8 Protein, Canine, Recombinant

chemokine (C-

Canine E. coli
IL-8/CXCL8 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9.2 kDa and the accession number is P41324.
TMPY-03480 IL-8/CXCL8 Protein, Rhesus, Recombinant

白介素,chemokine (C

Rhesus E. coli
IL-8/CXCL8 Protein, Rhesus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9.3 kDa and the accession number is P67813.
TMPY-00753 IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99, hFc)

LECT,MONAP,IL-8,LYNAP,白细胞介素,<...

Human HEK293 Cells
IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.6 kDa and the accession number is A0A024RDA5.
TMPY-00755 IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99, hFc)

chemokine (C-

Human HEK293 Cells
IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35 kDa and the accession number is A0A024RDA5.
TMPJ-00760 CXCL7 Protein, Human, Recombinant

SCYB7,C-X-<...

Human E. coli
Human Chemokine (C-X-C motif) Ligand 7 (CXCL7), also known as neutrophil activating peptide 2 (NAP-2), is a member of the CXC chemokines containing an ELR domain (Glu-Leu-Arg tripeptide motif). Similar to other ELR domain containing CXC chemokines, such as IL-8 and the GRO proteins, CXCL7 binds CXCR2, chemoattracts and activates neutrophils. CXCL7, Connective Tissue Activating Protein III (CTAPIII) and βthrombogulin (βTG), are proteolytically processed carboxylterminal fragments of platelet basi...
TMPJ-01060 CXCL6 Protein, Human, Recombinant (His)

SCYB6,Chemokine...

Human HEK293 Cells
Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. It is a potent neutrophil chemotactic and activating factor and it exhibits extensive similarity to other CXC chemokines such as IL-8 and ENA-78. CXCL6 can promote the release of MMP-9 from granulocytes indicating its potential role as an inflammatory mediator. It functionally uses both of the IL-8/CXCL8 receptors to chemoattract neutrophils but that is structurally most related to epithelial cell...
TMPY-04123 CEACAM1 Protein, Human, Recombinant (His & hFc)

CEACAM‑1,c<...

Human HEK293 Cells
CEACAM1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 71.4 kDa and the accession number is P13688-8.
TMPH-01705 Mucin-1/MUC1 Protein, Human, Recombinant (His)

Human E. coli
Mucin-1/MUC1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.2 kDa and the accession number is P15941-8.
TMPJ-00808 CD45RA Protein, Human, Recombinant (His)

PTPRC,CD45R,C

Human HEK293 Cells
CD45RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-135 KDa and the accession number is P08575-8.
TMPJ-00828 Tau-F Protein, Human, Recombinant

Neurofibrillary tangle protein,Paired helic

Human E. coli
Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. The tau proteins are the product of alternative splicing from a single gene that in humans is designated MAPT. When tau proteins are def...
TMPY-00717 CEACAM1 Protein, Human, Recombinant (His)

CEACAM‑1,BGP1,BGP,

Human HEK293 Cells
CEACAM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.8 kDa and the accession number is P13688-8.
TMPY-06707 Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His)

ADMCKD,PEMT,KL-6,ADMCKD1...

Human HEK293 Cells
Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.49 kDa and the accession number is P15941-8.
TMPJ-01330 CD299 Protein, Human, Recombinant (His & Flag)

DC-SIGNR,L-SIGN,CD299,

Human HEK293 Cells
CD299 is also known as DC-SIGNR and CLEC4M, is a type II integral membrane protein. DC-SIGNR exists as a homotetramer, and the tandem repeat domain, also called neck domain, mediates oligermerization. Multiple human DC-SIGN/CD209 splice forms exist, generating both membrane-bound and soluble forms. DC-SIGNR is ragarded as a pathogen-recognition receptor involved in peripheral immune surveillance in liver, and probably mediate the endocytosis of pathogens which are subsequently degraded in lysoso...
TMPY-00668 APP/Protease nexin-II Protein, Human, Recombinant (hFc)

CTFγ,amyloid beta (A4) prec

Human HEK293 Cells
APP/Protease nexin-II Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 101 kDa and the accession number is P05067-8.
TMPK-01450 HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

KRAS1,MHC,K-RAS4B,KRAS,C...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01456 HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi)

KRAS2,NS,MHC,C-K-RAS,KRA...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01451 HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi)

NS3,K-RAS4A,K-Ras 2,NS,KRAS1,RASK2,MHC,KI-...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.

重组蛋白

IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99)
Cat.No: TMPY-00472
Species: Human
Expression System: E. coli
IL-8/CXCL8 Protein, Human, Recombinant (His)
Cat.No: TMPY-04726
Species: Human
Expression System: P. pastoris (Yeast)
IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99)
Cat.No: TMPY-00754
Species: Human
Expression System: HEK293 Cells
Dengue virus DENV-2 (strain New Guinea C) NS5 (methyltransferase domain)/Nonstructural protein 5 Protein (His)
Cat.No: TMPY-00279
Species: DENV
Expression System: E. coli
IL-8/CXCL8 Protein, Canine, Recombinant
Cat.No: TMPY-03022
Species: Canine
Expression System: E. coli
IL-8/CXCL8 Protein, Rhesus, Recombinant
Cat.No: TMPY-03480
Species: Rhesus
Expression System: E. coli
IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99, hFc)
Cat.No: TMPY-00753
Species: Human
Expression System: HEK293 Cells
IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99, hFc)
Cat.No: TMPY-00755
Species: Human
Expression System: HEK293 Cells
CXCL7 Protein, Human, Recombinant
Cat.No: TMPJ-00760
Species: Human
Expression System: E. coli
CXCL6 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01060
Species: Human
Expression System: HEK293 Cells
CEACAM1 Protein, Human, Recombinant (His & hFc)
Cat.No: TMPY-04123
Species: Human
Expression System: HEK293 Cells
Mucin-1/MUC1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01705
Species: Human
Expression System: E. coli
CD45RA Protein, Human, Recombinant (His)
Cat.No: TMPJ-00808
Species: Human
Expression System: HEK293 Cells
Tau-F Protein, Human, Recombinant
Cat.No: TMPJ-00828
Species: Human
Expression System: E. coli
CEACAM1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00717
Species: Human
Expression System: HEK293 Cells
Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His)
Cat.No: TMPY-06707
Species: Human
Expression System: HEK293 Cells
CD299 Protein, Human, Recombinant (His & Flag)
Cat.No: TMPJ-01330
Species: Human
Expression System: HEK293 Cells
APP/Protease nexin-II Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00668
Species: Human
Expression System: HEK293 Cells
HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01450
Species: Human
Expression System: HEK293 Cells
HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01456
Species: Human
Expression System: HEK293 Cells
HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01451
Species: Human
Expression System: HEK293 Cells
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